Weight loss that treats the biology, not the blame.
Lab-driven medical weight loss with GLP-1 therapy and provider monitoring, built by a licensed clinician for how your body actually works. Reviewed online, adjusted over time.
Start my weight loss assessment
Why weight loss is biology, not willpower.
If diets worked long-term, you would not be reading this. The body defends its weight with hormones and metabolism. The right approach starts with what your bloodwork shows, then treats the actual drivers.
Your metabolic set point
Your body defends a weight range. Diet alone signals starvation, so metabolism slows and hunger climbs. This is biology, not a lack of discipline.
Insulin resistance
When cells stop responding to insulin, blood sugar spikes and the body stores fat instead of burning it. Breaking this cycle is often the real unlock.
Hormones and thyroid
Thyroid, cortisol, and sex hormones all shape how you store and burn fat. A symptom-only approach misses the markers that actually drive the scale.
Appetite signaling
Hunger and fullness are hormonal conversations between your gut and brain. GLP-1 therapy changes that conversation so eating less stops being a fight.
A licensed clinician confirms what is driving your weight with lab testing before recommending treatment. If medication is not the right answer for you, they will tell you, and help you find the right path.
Four steps from curious to optimized.
Take the assessment
2 minutes. Goals, symptoms, medical history.
Clinical-grade intake reviewed by a provider, not a template.
Comprehensive labs
50+ markers. At-home kit or Quest / Labcorp.
Hormones, thyroid, metabolic, inflammation, micronutrients. HSA/FSA eligible.
Consult with your provider
HIPAA video call. AI-transcribed. Recapped.
Licensed clinician reviews your labs, builds your protocol, answers questions.
Delivered in 48 hours
Discreet packaging. Refills ship automatically.
Compounding pharmacy partner. Free 2-day shipping. Cancel anytime.
How GLP-1 therapy works.
Appetite regulation
GLP-1 receptor agonists mimic your body's natural incretin hormones, signaling fullness to the brain. Many patients report meaningfully reduced hunger and fewer cravings in the first few weeks.
Insulin sensitivity
GLP-1 therapy improves how your body processes glucose, reducing post-meal blood sugar spikes and helping break the insulin-resistance cycle that drives fat storage.
Metabolic reset
Over several months, GLP-1 therapy can shift your metabolic set point. Paired with provider-guided nutrition and muscle support, the goal is sustainable body-composition change. Individual results vary.
FDA-approved GLP-1 medications.
For the full breakdown of semaglutide and tirzepatide, including clinical-trial detail, see our GLP-1 therapy page.
Semaglutide
Wegovy, Ozempic
GLP-1 receptor agonist
FDA-approved for chronic weight management in adults with BMI 30+, or 27+ with a weight-related condition. Dose is titrated over several weeks to limit GI side effects. Your clinician decides if it fits your labs and history.
Tirzepatide
Mounjaro, Zepbound
Dual GIP / GLP-1 receptor agonist
A dual-agonist option that provides additional metabolic benefit beyond GLP-1 alone. FDA-approved for chronic weight management and type 2 diabetes. Appropriateness and dose are a clinical decision based on your bloodwork.
Which medication is appropriate, and at what dose, is a clinical decision your provider makes from your bloodwork and history. Individual results vary.
Not a prescription mill. A care relationship.
A real clinician, on video
You speak face to face with a licensed clinician before anything is prescribed. Not a chatbot, not a one-way questionnaire.
Lab-driven protocols
We run a comprehensive metabolic panel before starting and recheck over time. Your plan is titrated to your biology, not an off-the-shelf dose.
Muscle-preservation support
Rapid weight loss can cost lean muscle. Your provider pairs your protocol with protein and resistance guidance, and layers adjunct support when clinically appropriate.
Root-cause first
Thyroid, insulin, cortisol, and hormones all move the scale. We look for the driver, not just hand you the medication.
Transparent pricing
You pay for care. If a treatment is prescribed, the pharmacy bills brand-name medication separately at its published cash-pay price, with no KAYU markup.
We say no when it is right
A clinician declines or adjusts treatment when weight-loss medication is not the right answer, and tells you what would be instead.
A realistic timeline.
First few weeks
Appetite usually quiets first. Your provider titrates slowly to limit nausea and checks in as you settle into the protocol.
Weeks 4 to 12
Measurable change typically begins as you approach your maintenance dose. Follow-up labs confirm your metabolic markers are moving the right way.
Months 3 and beyond
The focus shifts to sustainable body composition and protecting lean mass. Your provider adjusts your plan around your labs and how you feel. Individual results vary.
Real clinicians, not a call center.
Your protocol is built and monitored by a licensed clinician, the same people who designed KAYU's care model. Named, credentialed, and accountable for your results.

Narine Chilyan
Clinical Director · Functional & Preventive Medicine

Dr. Aram Mkhitarian
Medical Director · Integrative Medicine

Kiana Golfeiz
Aesthetics · Longevity · Regenerative
How KAYU compares.
A general comparison of care models. Specific offerings vary by provider.
Simple, transparent membership.
Pay for care, not markups. Your membership covers provider access, monitoring, and quarterly labs - your GLP-1 medication is billed separately by a licensed pharmacy at its published cash-pay price. No insurance required, HSA and FSA eligible, cancel anytime.
Pay for the visit, no membership.
- 60-minute video consult with a licensed clinician
- A personalized plan if treatment is appropriate
- Prescription sent to a licensed pharmacy
- Credit applies to your first month if you upgrade
Ongoing care, monitoring, and 10% off.
- Everything in Consult
- Ongoing provider oversight and dose titration
- Quarterly lab panel, KAYU pays Quest direct
- 10% off compounded medication, unlimited messaging
Full optimization with bloodwork included.
- Everything in Root
- Comprehensive hormone + metabolic panel included
- Broader multi-system optimization when appropriate
- 20% off medication, priority scheduling
Brand-name GLP-1 medication (semaglutide, tirzepatide) is billed separately by a licensed pharmacy at its published cash-pay price, only after a clinician approves it. KAYU adds no markup.
Medical weight loss FAQ.
Who is eligible for medical weight loss?
GLP-1 medications are FDA-approved for adults with a BMI of 30 or higher, or 27 or higher with a weight-related condition such as high blood pressure, type 2 diabetes, high cholesterol, or sleep apnea. Your KAYU clinician makes the final determination from your full history and labs.
What is the difference between semaglutide and tirzepatide?
Semaglutide is a GLP-1 receptor agonist. Tirzepatide is a dual GIP and GLP-1 agonist, which adds a second metabolic pathway. Which one fits you, and at what dose, is a clinical decision your provider makes from your bloodwork and goals.
What are the common side effects?
The most common are gastrointestinal, such as nausea, constipation, and diarrhea, usually during dose escalation. KAYU uses slow titration and supportive measures to limit them. Most patients find side effects ease as they reach their maintenance dose.
Will I regain the weight if I stop?
Some regain can occur after stopping. KAYU works to build sustainable habits during treatment, monitors your metabolic markers, and designs a gradual taper rather than an abrupt stop. Some patients move to a lower maintenance dose long-term.
How do you protect against muscle loss?
Rapid weight loss can reduce lean mass. Your provider recommends targeted protein intake, resistance-training guidance, and adjunct support when clinically appropriate, and tracks body composition over time.
Does KAYU prescribe compounded GLP-1?
KAYU prescribes brand-name, FDA-approved medications dispensed by licensed pharmacies. Your safety is the priority, and your clinician will tell you exactly what is being prescribed.
How quickly will I see results?
Many patients notice reduced appetite within the first week or two. Measurable weight change typically begins around week 4 to 6 and continues as you reach your maintenance dose. Individual results vary, and your provider monitors progress throughout.
Can I use HSA or FSA funds?
Yes. Weight-loss medication prescribed for a medical diagnosis is generally HSA and FSA eligible. KAYU provides the documentation your benefits administrator needs. No insurance is required to start.
Can I cancel anytime?
Yes. There is no long-term lock-in. You can cancel your membership at any time, and you are only charged for medication after a licensed clinician approves it.
Ready to feel rooted?
Two minutes to the assessment. One week to your first consult. A protocol built on your bloodwork from a provider who knows your name.