The science behind your treatment plan.
Mechanism-of-action explainers, clinical evidence reviews, and treatment plan guides - written for the informed patient, reviewed by KAYU providers.
GLP-1 Receptor Agonists: Mechanism of Action
Semaglutide and tirzepatide are reshaping metabolic medicine. GLP-1 receptor agonists reduce appetite via hypothalamic signaling, enhance insulin secretion through incretin pathways, slow gastric emptying, and demonstrate cardiovascular and neuroprotective benefits. This review covers receptor pharmacology, large clinical programs for prescription weight-loss injectables (STEP, SURMOUNT), and emerging research directions.
Semaglutide: How It Works, Dosing, and What to Expect
How semaglutide reduces appetite, the standard titration schedule, side effects, and the compounded-versus-brand question.
Tirzepatide: Dual-Receptor Mechanism, Dosing, and Results
Why tirzepatide's two receptors can produce more weight loss, the full titration chart, side effects, and compounded versus brand.
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