The science behind your protocol.
Mechanism-of-action explainers, clinical evidence reviews, and protocol guides — written for the informed patient, reviewed by KAYU physicians.
How BPC-157 Promotes Tissue Repair
BPC-157 (Body Protection Compound-157) is a 15-amino-acid peptide derived from human gastric juice. It accelerates healing through angiogenesis, upregulation of VEGF and nitric oxide pathways, and modulation of the GH receptor. This article reviews the mechanism of action, key preclinical studies, and clinical implications for tendon, ligament, gut, and musculoskeletal repair.
Growth Hormone Secretagogues: CJC-1295 + Ipamorelin
CJC-1295 (a GHRH analog) and Ipamorelin (a selective ghrelin receptor agonist) work synergistically to produce pulsatile growth hormone release that mimics physiological patterns. Unlike exogenous GH, this combination preserves the hypothalamic-pituitary feedback loop. We cover GHRH receptor binding, GH pulse dynamics, IGF-1 response, and safety data.
GLP-1 Receptor Agonists: Mechanism of Action
Semaglutide and tirzepatide are reshaping metabolic medicine. GLP-1 receptor agonists reduce appetite via hypothalamic signaling, enhance insulin secretion through incretin pathways, slow gastric emptying, and demonstrate cardiovascular and neuroprotective benefits. This review covers receptor pharmacology, clinical trial data (STEP, SURMOUNT), and emerging off-label applications.
Ready to feel rooted?
Two minutes to the assessment. One week to your first consult. A protocol built on your bloodwork from a physician who knows your name.