Testosterone Replacement Therapy

Testosterone, optimized for how you want to feel.

Lab-driven testosterone therapy built by a licensed clinician for your biology, not an off-the-shelf protocol. Reviewed online, monitored over time.

Start my TRT assessment
Active man in his forties resting after a run on a wooded trail
Licensed clinicians
Lab-driven protocols
Shipped to your door
No insurance required

Three ways KAYU helps men, built around your goal.

Restore testosterone, raise it while protecting fertility, or simply perform when it counts. Your provider builds the right protocol from your bloodwork, and you can combine them when it makes sense.

Restore

Testosterone Replacement

Men with clinically low testosterone

Bring testosterone back to an optimal range directly. The most direct path to steadier energy, libido, strength, and recovery.

InjectableCreamHCG support
Protect fertility

Enclomiphene

Men who want higher T without losing fertility

An oral that signals your body to raise its own testosterone, so natural production and fertility stay intact. No injections.

OralFertility-friendlyDaily
Performance

ED Treatment

Men who want dependable erections

Compounded sildenafil or tadalafil, dosed to you, for reliable erectile function. Works on its own or alongside hormone therapy.

SildenafilTadalafilAs needed or daily
Find your protocol

Not sure which fits? The assessment takes about two minutes, and a licensed clinician decides what is appropriate from your labs.

What low testosterone actually feels like.

Testosterone tends to decline gradually as men age, and low levels can quietly affect energy, mood, body composition, and sex drive. Symptoms alone don't confirm it, which is why a diagnosis is built on bloodwork and a clinician's review, never a guess.

Low energy

Persistent fatigue that sleep doesn't fix, and a harder time getting through the day.

Reduced libido

A noticeable drop in sex drive, or changes in erectile function.

Brain fog

Trouble concentrating, slower recall, and a duller sense of motivation.

Muscle and strength

Difficulty building or holding muscle despite training the way you used to.

Mood changes

Lower mood, irritability, or a flatter emotional baseline than feels like you.

Poor sleep and recovery

Lighter sleep, slower recovery from workouts, and stubborn body fat.

A licensed clinician confirms low testosterone with lab testing before recommending treatment. If your symptoms point somewhere else, they'll tell you, and help you find the right path.

How KAYU works

Four steps from curious to optimized.

01

Take the assessment

2 minutes. Goals, symptoms, medical history.

Clinical-grade intake reviewed by a provider, not a template.

02

Comprehensive labs

50+ markers. At-home kit or Quest / Labcorp.

Hormones, thyroid, metabolic, inflammation, micronutrients. HSA/FSA eligible.

03

Consult with your provider

HIPAA video call. AI-transcribed. Recapped.

Licensed clinician reviews your labs, builds your protocol, answers questions.

04

Delivered in 48 hours

Discreet packaging. Refills ship automatically.

Compounding pharmacy partner. Free 2-day shipping. Cancel anytime.

No commitmentHSA / FSA eligibleCancel anytimeFree 2-day shippingLicensed clinicians

Your hormones, balanced and monitored.

01

Restore an optimal range

When bloodwork confirms low testosterone, therapy brings levels back into a healthy range your provider targets to how you want to feel. Depending on your case, that may be injectable testosterone, a topical, or a medication that prompts your own production.

02

Keep the rest in balance

Testosterone doesn't work alone. Your provider manages estrogen conversion and supports natural signaling with medications like anastrozole or HCG when your labs show it's needed, so one number doesn't move at the expense of another.

03

Fertility-aware by design

Standard testosterone therapy can lower sperm production. If fertility matters to you, tell your provider. A licensed clinician can build a protocol around enclomiphene or HCG that supports your own production instead.

How enclomiphene works

Raise your testosterone without replacing it.

TRT adds testosterone from the outside. Enclomiphene works from the inside, switching your body's own production back on. Here is the path it takes.

1
Your brain

The signal starts in your brain.

Enclomiphene gently blocks estrogen's feedback at the hypothalamus, so your brain reads the cue to make more testosterone.

2
Your pituitary

It tells the pituitary to act.

Your pituitary releases more LH and FSH, the messenger hormones that signal your testes to switch production on.

3
Your testes

You make your own testosterone.

Your testes raise their natural testosterone output and keep sperm production running, so fertility stays intact.

The result is higher testosterone your body produced itself, with no injected hormone and your fertility protected.

TRT

Replaces your testosterone

  • Adds testosterone from outside the body
  • Your own production can switch off
  • Fertility can decline during use
  • Injection or topical cream

Enclomiphene

Raises your own testosterone

  • Signals your body to make more itself
  • Your natural hormone system keeps running
  • Designed to preserve fertility
  • A simple once-daily oral

Enclomiphene is prescribed off-label and is not FDA-approved for raising testosterone in men. Whether it is appropriate, and at what dose, is a clinical decision your provider makes from your bloodwork and goals. Individual results vary.

Medications a provider may consider for you.

Testosterone Cypionate

Injectable testosterone that restores levels to an optimal range when a clinician determines it's appropriate.

Injectable

Enclomiphene

Encourages your body to raise its own testosterone while preserving fertility.

Oral

HCG

Helps maintain testicular function and natural production during therapy.

Injectable

Anastrozole

Manages estrogen conversion when bloodwork shows it's needed.

Oral

Testosterone Cream

Topical option for men who prefer a daily application over injections.

Topical

Clomiphene

Stimulates the body's own hormone signaling as an alternative path for select cases.

Oral

Which medications are appropriate, and at what dose, is a clinical decision your provider makes from your bloodwork and symptoms. Some products are compounded, are not FDA-approved, and require a prescription. Individual results vary.

Why men choose KAYU for testosterone therapy.

A real clinician, on video

You speak face to face with a licensed clinician before anything is prescribed. Not a chatbot, not a one-way questionnaire.

Lab-driven protocols

We confirm low testosterone with comprehensive bloodwork and titrate your protocol to your biology, then recheck your levels over time.

Fertility-friendly options

If preserving fertility matters, your provider can build around enclomiphene or HCG rather than defaulting to standard testosterone.

Monitored over time

Your provider tracks follow-up labs and how you feel, adjusting your protocol as you go. Message your care team any time.

Transparent pricing

You pay for care. If a treatment is prescribed, the pharmacy bills medication separately at cost, with no KAYU markup.

We say no when it's right

A clinician declines or adjusts treatment when testosterone therapy isn't the right answer, and tells you what would be instead.

A realistic timeline.

First few weeks

Many men first notice changes in energy, mood, and libido. Your provider checks in and answers questions as you settle into the protocol.

Weeks 6 to 12

Follow-up bloodwork confirms your levels are in range. Your provider fine-tunes your dose based on your labs and how you feel.

Months 3 and beyond

Changes in strength and body composition build with consistent, monitored treatment alongside training and nutrition.

Timelines are general and not a promise of results. Individual results vary, and your provider monitors your progress and adjusts your protocol along the way.

Your care team

Real clinicians, not a call center.

Your protocol is built and monitored by a licensed clinician, the same people who designed KAYU's care model. Named, credentialed, and accountable for your results.

Narine Chilyan, DNP, AGNP-C

Narine Chilyan

DNP, AGNP-C

Clinical Director · Functional & Preventive Medicine

HormonesFunctional MedicineWeight Loss
Dr. Aram Mkhitarian, DO

Dr. Aram Mkhitarian

DO

Medical Director · Integrative Medicine

OsteopathicIntegrativePrimary Care
Kiana Golfeiz, PA-C

Kiana Golfeiz

PA-C

Aesthetics · Longevity · Regenerative

PeptidesAestheticsRegenerative

How KAYU compares.

KAYU
Typical telehealth
Traditional clinic
Confirms low T with bloodwork first
Face-to-face video consult with a licensed clinician
Fertility-preserving protocol options
Ongoing lab monitoring and dose adjustments
Medication shipped to your door
Transparent pricing, no insurance required

A general comparison of care models. Specific offerings vary by provider.

Pay for care, not markups.

You pay for your provider and care. If medication is prescribed, the pharmacy bills it separately at cost, with no KAYU markup. No insurance required.

Consult

$49.99 one-time

Pay for your visit, no membership.

  • Licensed clinician video consultation
  • Personalized TRT plan if appropriate
  • Prescription sent to a licensed pharmacy
  • Medication billed separately at cost
Get started
Most chosen

Root

$199 per month

Ongoing care and monitoring, 10% off care.

  • Everything in Consult
  • Ongoing provider oversight and titration
  • Follow-up lab review built in
  • Unlimited secure messaging with your care team
Get started

Branch

$499 per month

Full hormone optimization with bloodwork included.

  • Everything in Root
  • Comprehensive hormone panel included
  • Broader hormone optimization when appropriate
  • Priority scheduling with your provider
Get started

Testosterone therapy FAQ.

What is TRT and how does it work?

Testosterone replacement therapy restores testosterone to a healthy, optimal range when your body isn't producing enough on its own. Depending on your case and goals, a licensed clinician may use injectable testosterone, a topical, or a medication like enclomiphene that prompts your own production, along with support medications to keep the rest of your hormones in balance.

What are the symptoms of low testosterone?

Common symptoms include persistent low energy, reduced libido, brain fog, difficulty building or holding muscle, low mood, poor sleep, and slower recovery. These symptoms overlap with other conditions, which is why bloodwork and a licensed clinician's review matter before anything is prescribed.

Do I need bloodwork, and how do I know which protocol is right for me?

Yes. Testosterone replacement is a clinical decision built on data, not symptoms alone. A licensed clinician reviews your labs, including testosterone, estradiol, and related markers, to confirm low testosterone and choose a protocol that fits you, then monitors your levels over time. Which medications are appropriate is the clinician's call, not yours to pick from a menu.

Is TRT safe? What are the side effects?

A licensed clinician reviews your health history and bloodwork before anything is prescribed, and declines or adjusts treatment if it isn't appropriate for you. Like any therapy, TRT has potential side effects your provider reviews with you, and ongoing lab monitoring is part of staying safe. You can message your care team any time with questions. Individual results and risks vary.

Will TRT affect my fertility?

Standard testosterone therapy can lower sperm production. If preserving fertility matters to you, tell your provider. A licensed clinician can build a protocol around medications like enclomiphene or HCG that support your own production, or recommend an alternative path.

Can I do this entirely online without a clinic visit?

Yes. Your assessment, video consult, and follow-ups happen online, and medication ships to your door. Bloodwork is done through an at-home kit or a nearby Quest or Labcorp location. Everything is reviewed by a licensed clinician.

How quickly will I notice a difference?

Many men notice improvements in energy, mood, and libido within the first few weeks, with changes in body composition and strength building over several months of consistent, monitored treatment. Your provider adjusts your protocol based on how you feel and what your follow-up labs show. Individual results vary.

How does billing work, and do you take insurance or HSA / FSA?

You pay for your provider review and care. If a treatment is prescribed, the pharmacy bills for your medication separately, at cost, with no KAYU markup. No insurance is required, and many patients use HSA or FSA funds toward eligible care. You're only charged for medication after a licensed clinician approves it.

Who's a candidate, and can I cancel anytime?

Men with confirmed low testosterone and related symptoms are typical candidates, but it isn't right for everyone. A licensed clinician reviews your labs, symptoms, and health history to determine whether testosterone therapy, or an alternative, is the better fit. There's no long-term commitment, and you can cancel anytime.

Your next move

Ready to feel rooted?

Two minutes to the assessment. One week to your first consult. A protocol built on your bloodwork from a provider who knows your name.

✓ No credit card✓ 7-day guarantee✓ Cancel anytime✓ HSA / FSA eligible