GLP-1 therapy for sustainable weight loss.
Provider-prescribed semaglutide (Wegovy®) and tirzepatide (Mounjaro®) with lab monitoring, video consults, and peptide support to protect lean muscle. Not a questionnaire - a real medical relationship.
Start your weight loss consult
How GLP-1 therapy works.
Appetite suppression
GLP-1 receptor agonists mimic your body's natural incretin hormones, signaling fullness to the brain. Patients report significantly reduced hunger and fewer food cravings within the first 2-4 weeks of treatment.
Insulin sensitivity
GLP-1s enhance your pancreatic beta-cell response, improving how your body processes glucose. This reduces blood sugar spikes after meals and helps break the cycle of insulin resistance that drives fat storage.
Metabolic reset
Over 12-16 weeks, GLP-1 therapy shifts your metabolic set point. Gastric emptying slows, reducing caloric absorption. Combined with provider-guided nutrition, patients achieve sustainable body composition changes - not just water weight.
FDA-approved GLP-1 medications.
Semaglutide
Wegovy® / Ozempic®
GLP-1 receptor agonist
In the STEP 1 clinical trial, patients lost an average of 14.9% of body weight over 68 weeks compared to 2.4% with placebo. STEP 3 showed 16% weight loss when combined with intensive behavioral therapy.
FDA-approved for chronic weight management in adults with BMI ≥ 30 (or ≥ 27 with a weight-related comorbidity). Dose is titrated over 16-20 weeks to minimize GI side effects.
Tirzepatide
Mounjaro® / Zepbound®
Dual GIP/GLP-1 receptor agonist
The SURMOUNT-1 trial demonstrated up to 22.5% body weight loss at the highest dose over 72 weeks - the most significant weight reduction achieved by any anti-obesity medication to date.
FDA-approved for type 2 diabetes (Mounjaro®) and chronic weight management (Zepbound®). The dual-agonist mechanism provides additional metabolic benefits beyond GLP-1 alone.
Why patients choose KAYU for GLP-1 therapy.
Clinician video consult
You speak face-to-face with a licensed clinician - not a chatbot, not a questionnaire. Your provider reviews your labs, medical history, and goals before prescribing anything.
Lab-driven protocols
We order comprehensive metabolic panels, thyroid function, and insulin markers before starting. Your dose is titrated to YOUR biology, with labs rechecked at 8 and 16 weeks.
AI-assisted monitoring
Between consults, KAYU's AI tracks your progress, flags concerning trends, and adjusts recommendations in real time. Your provider reviews every alert.
Muscle preservation support
GLP-1 therapy can cause lean mass loss. KAYU pairs your protocol with recovery-support peptides and protein guidance - your provider decides whether to layer adjuncts based on your labs and goals.
No hidden fees
Your Root membership covers provider access, quarterly bloodwork (KAYU pays Quest direct), AI monitoring, and ongoing protocol adjustments. Brand-name GLP-1 medication is billed separately by a licensed pharmacy at its published cash-pay price. Upgrade to Branch ($499/mo) any time if you want hormones included.
Real clinicians, not a call center.
Your protocol is built and monitored by a licensed clinician, the same people who designed KAYU's care model. Named, credentialed, and accountable for your results.
Narine Chilyan
Clinical Director · Functional & Preventive Medicine
Dr. Aram Mkhitarian
Medical Director · Integrative Medicine
Kiana Golfeiz
Aesthetics · Longevity · Regenerative
Know exactly what you'll pay, before you start.
Most GLP-1 programs make the real cost hard to find. KAYU itemizes it: one flat membership for your care, and the medication billed straight from the pharmacy with no markup.
- Monthly price. One flat Root membership at $199. It does not climb as your dose climbs.
- Medication. Billed straight from a licensed pharmacy at cash-pay. KAYU adds no markup.
- Bloodwork. Quarterly panel included. KAYU pays Quest directly.
- Your provider. A named licensed clinician oversees every titration.
- Commitment. Cancel anytime. No lock-in.
- Bottom line. Itemized and clear before you start.
- Monthly price. Tiered plans that go up as your dose goes up.
- Medication. Often bundled or marked up, so the real drug cost is hard to isolate.
- Bloodwork. An add-on, or skipped to keep the headline price low.
- Your provider. Whoever is on shift, often without continuity.
- Commitment. Multi-month plans, frequently paid upfront.
- Bottom line. Spread across fine print, easy to misread.
KAYU details reflect the Root membership. “The usual way” describes pricing practices common across direct-to-consumer GLP-1 programs, not any single provider. Medication is dispensed by a licensed pharmacy at its published cash-pay price.
Simple, transparent membership.
Pay for care, not markups. Your membership covers provider access, monitoring, and quarterly labs - your GLP-1 medication is billed separately by a licensed pharmacy at its published cash-pay price. No insurance required, HSA and FSA eligible, cancel anytime.
Pay for the visit, no membership.
- 60-minute video consult with a licensed clinician
- A personalized plan if treatment is appropriate
- Prescription sent to a licensed pharmacy
- Credit applies to your first month if you upgrade
Ongoing care, monitoring, and 10% off.
- Everything in Consult
- Ongoing provider oversight and dose titration
- Quarterly lab panel, KAYU pays Quest direct
- 10% off compounded medication, unlimited messaging
Full optimization with bloodwork included.
- Everything in Root
- Comprehensive hormone + metabolic panel included
- Broader multi-system optimization when appropriate
- 20% off medication, priority scheduling
Brand-name GLP-1 medication (semaglutide, tirzepatide) is billed separately by a licensed pharmacy at its published cash-pay price, only after a clinician approves it. KAYU adds no markup. Upgrade to Branch any time for hormones included.
GLP-1 therapy FAQ.
Who is eligible for GLP-1 therapy?
GLP-1 medications are FDA-approved for adults with a BMI of 30 or higher, or a BMI of 27+ with at least one weight-related condition (hypertension, type 2 diabetes, high cholesterol, sleep apnea). Your KAYU provider makes the final determination based on your full medical history and lab results.
What are the common side effects?
The most common side effects are gastrointestinal - nausea, constipation, and diarrhea - typically during dose escalation. KAYU mitigates this with slow titration schedules and supportive medications when needed. Most patients report side effects diminish significantly by week 8.
How quickly will I see results?
Most patients notice appetite reduction within the first 1-2 weeks. Measurable weight loss typically begins by week 4-6 and accelerates through months 3-6 as you reach your maintenance dose. Clinical trials show peak weight loss at 12-18 months of consistent use.
Will I gain the weight back if I stop?
Studies show that some weight regain occurs after discontinuation. KAYU addresses this by building sustainable habits during treatment, monitoring metabolic markers, and designing a gradual taper protocol rather than abrupt cessation. Some patients transition to maintenance doses long-term.
How does KAYU help preserve muscle mass?
Rapid weight loss can reduce lean muscle. Your KAYU provider recommends targeted protein intake (typically 1g per pound of goal body weight), may add adjunct peptide support based on your labs, and monitors lean mass via body composition tracking.
Can I use HSA or FSA funds?
Yes. GLP-1 medications prescribed for a medical diagnosis (obesity, type 2 diabetes) are eligible for HSA and FSA reimbursement. KAYU provides the documentation your benefits administrator needs.
What if GLP-1 therapy isn't right for me?
Your provider may recommend alternative approaches - thyroid optimization, metabolic peptides, or hormone balancing - depending on your labs. KAYU never prescribes GLP-1 when the root cause is something else entirely. If you're not a candidate, we tell you why and what we'd do instead.
Is this compounded semaglutide?
KAYU prescribes brand-name, FDA-approved medications (Wegovy®, Ozempic®, Mounjaro®, Zepbound®) dispensed by licensed pharmacies. We do not prescribe compounded semaglutide or tirzepatide. Your safety is non-negotiable.
Ready to feel rooted?
Two minutes to the assessment. One week to your first consult. A protocol built on your bloodwork from a provider who knows your name.